Prepared Long Format Data
Wide Format Data (Pre-Interpolation)
Filled internal missing values using linear interpolation
Based on [Post-Interpolation Wide Format] data, split by defined time periods
Complete interpolated wide format data (used for 24-hour calculations)
Patient Metric Overview (Based on 24h Unified Limits Results)
Key Metrics Overview (24h Unified Limits)
Statistics Summary (24h Unified Limits)
Metric Trend Chart (Uses Unified 24h Limits & Background)
Time Distribution (24h Unified Limits)
Burden Metrics (24h Unified Limits)
Variability Metrics (24h Unified Limits, vs Reference)
Metric Trend Chart (Differentiated Day/Night Limits & Background)
24h (Segmented Limits) Calculation Results:
Note: The following charts are based on combined daytime and nighttime data, using the respective target limits for each period.
Key Metrics Overview (24h Segmented Limits)
Statistics Summary (24h Segmented Limits)
Time Distribution (24h Segmented Limits)
Burden Metrics (24h Segmented Limits)
Variability Metrics (Overall 24h, vs Reference)
Key Metrics Overview (Daytime)
Statistics Summary (Daytime)
Metric Trend Chart (Same as 24h Segmented Limits View)
Time Distribution (Daytime)
Burden Metrics (Daytime)
Variability Metrics (Daytime, vs Reference)
Key Metrics Overview (Nighttime)
Statistics Summary (Nighttime)
Metric Trend Chart (Same as 24h Segmented Limits View)
Time Distribution (Nighttime)
Burden Metrics (Nighttime)
Variability Metrics (Nighttime, vs Reference)
ABPM Novel Metrics Analysis System User Guide
1. Load Data
- Use [Use Built-in Example Data] or [Select ABPM CSV File] to load data.
- Check [Data Format Requirements] in the sidebar.
- Preview in the [View Input Data] tab.
2. Define Day/Night Times
- Enter [Daytime Start Time] and [Nighttime Start Time] for Day1/Day2.
- Use [East Asia] or [Western] quick preset buttons.
3. Process Data
- Click the [1. Process Data] button.
- System performs: Cleaning & Validation -> Time Standardization -> Wide Data Conversion -> Linear Interpolation -> Period Segmentation .
- Intermediate data can be viewed in [Processed Data] and [Segmented Data].
- Buttons below are enabled upon success.
4. Set Target Ranges
- Set upper/lower limits for SBP/DBP/HR for [Daytime]/[Nighttime]/[24-Hour (Unified)].
- PP/MAP ranges are optional; if not filled, their TTR/Burden etc. won't be calculated.
- Use [Auto-Calculate PP/MAP Ranges] or [Apply Default Target Ranges].
- To fix custom ranges, click [Save & Lock Custom Ranges].
5. Calculate Metrics
- Click the [2. Calculate Metrics] button.
- The system uses the [Currently Displayed Target Ranges] to calculate the following metrics:
- Daytime Summary
- Nighttime Summary
- 24h (Unified Limits): Uses the 24h unified target range for the entire period.
- 24h (Segmented Limits): Combines daytime and nighttime data, but uses their respective target limits to calculate weighted 24-hour metrics (like TTR, Burden, etc.).
- Results are shown in the [Metric Calculation Results] tab under corresponding sub-tabs, and can be exported.
6. Visualization Analysis
- Select [Patient] and [Metric].
- View in [24h (Unified Limits)] / [24h (Segmented Limits)] / [Daytime] / [Nighttime] tabs:
- Overview & Summary (Based on corresponding calculation results).
- Trend Chart: [24h (Unified Limits)] tab shows unified limit background; [24h (Segmented Limits)] / [Daytime] / [Nighttime] tabs show differentiated day/night limit background.
- Time Distribution Chart (Based on corresponding calculation results).
- Burden Chart (Based on corresponding calculation results).
- Variability Chart (SD/ARV based on corresponding period data, vs reference values).
7. Metric Explanation
| Metric | Period (Result Tab) | Meaning | Notes/Significance |
|---|---|---|---|
| TTR | All Periods | Time in Target Range (%) | Proportion of time within target range, higher is better |
| TOTR | All Periods | Time Over Target Range (%) | Proportion of time above target range, lower is better |
| TUTR | All Periods | Time Under Target Range (%) | Proportion of time below target range, lower is better |
| hyper_Burden | All Periods | Hypertension/Hyper Burden (%) | High value burden (combines time & magnitude), lower is better |
| hypo_Burden | All Periods | Hypotension/Hypo Burden (%) | Low value burden (combines time & magnitude), lower is better |
| cumulative_Load | All Periods | Cumulative Load (%) | Cumulative load (Sa / Sd * 100) |
| Load | All Periods | Load (%) | Percentage of measurements above upper limit (based on interpolated data & period upper limit) |
| mean | All Periods | Mean Value | Average value (based on interpolated data for the period) |
| SD | All Periods | Standard Deviation | Standard deviation (sample), assesses volatility |
| CV | All Periods | Coefficient of Variation (%) | Coefficient of variation (SD / |Mean| * 100) |
| ARV | All Periods | Average Real Variability | Average of absolute differences between consecutive interpolated values |
| max_value | All Periods | Maximum Value | Maximum value (based on interpolated data for the period) |
| min_value | All Periods | Minimum Value | Minimum value (based on interpolated data for the period) |
| Delta | All Periods | Range (Max - Min) | Fluctuation range (based on interpolated data for the period) |
| AUC / Sd | All Periods | Area Under Curve | Total area under the curve (equal to Sd) |
| Ts1_total | All Periods | Time Over Upper Limit | Total time above upper limit (minutes) |
| Ts2_total | All Periods | Time Within Range | Total time within target range (minutes) |
| Ts3_total | All Periods | Time Below Lower Limit | Total time below lower limit (minutes) |
| Sa | All Periods | Area above Upper Limit | Area under curve for high values (for calculation) |
| Sc | All Periods | Area below Lower Limit | Area between low values and lower limit (for calculation) |
| Se | All Periods | Rectangular Area for Hyper | Rectangular area for high value time (for calculation) |
| Sf | All Periods | Rectangular Area for Hypo | Rectangular area for low value time (for calculation) |
About the Author & Version
Moran Li
Master of Clinical Medicine, Tongji University School of Medicine; Physician, Shanghai Tenth People's Hospital
Application Version: 1.0.0 (English Version, Updated: Apr 17, 2024)
Contact / Feedback / Suggestions: morethanlee@163.com